Kirsch lab

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Kirsch lab

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Principal Investigator

David G. Kirsch, MD, PhD

Director, Radiation Medicine Program, Princess Margaret Cancer Centre 

Head, Department of Radiation Oncology, University Health Network

Senior Scientist, Princess Margaret Cancer Centre 

Peter and Shelagh Godsoe Chair in Radiation Medicine 

Professor, Departments of Radiation Oncology & Medical Biophysics, University of Toronto

Follow Dr. Kirsch on Twitter here

Lab staff

Jasmine Wong, PhD

Sabelo Lukhele, PhD

Sabelo Lukhele, PhD

 Scientific Associate/Lab Manager


Jasmine studies the link between the loss of tumor suppressors and the derepression of transposable elements. 


email: Jasmine.Wong@uhn.ca


Sabelo Lukhele, PhD

Sabelo Lukhele, PhD

Sabelo Lukhele, PhD

Senior Scientific Associate


Sabelo studies tumour responses to radiation and immunotherapies, and mechanisms of tumour suppression and metastasis.


email: Sabelo.Lukhele@uhn.ca


Pardis Riahi

Sabelo Lukhele, PhD

Dennis Aquino

Research Technician


Pardis studies how revival stem cells promote intestinal regeneration following radiation injury. 


email: Pardis.Riahi@uhn.ca

Dennis Aquino

Sabelo Lukhele, PhD

Dennis Aquino

Mouse colony manager


Dennis performs a variety of technical duties involved in basic research through advanced breeding colony management.


email: Benigno.Aquino@uhn.ca

Post-doctoral fellows

Ryo Miyamoto

Peter Hendrickson

Ryo Miyamoto

Post-doctoral Fellow


Ryo uses mouse models and functional genomics to investigate mechanisms and therapeutic targets of epithelioid sarcoma.


email: Ryo.Miyamoto@uhn.ca

Mardi Fink

Peter Hendrickson

Ryo Miyamoto

Post-doctoral fellow


Mardi studies how revival stem cells promote intestinal regeneration following radiation injury. 


email: MardiLilly.Fink@uhn.ca

Peter Hendrickson

Peter Hendrickson

Peter Hendrickson

Radiation Oncology Fellow


Peter studies mechanisms of disease and genetic dependencies/vulnerabilities in CIC::DUX4 sarcoma. 

email: Peter.Hendrickson@duke.edu

Graduate students

MaKenna Browne

MaKenna Browne

MaKenna Browne

Visiting PhD candidate


MaKenna studies mechanisms underlying CIC::DUX4 driven sarcomagenesis.

email: MakennaRenee.Browne@uhn.ca

Risha Banerjee

MaKenna Browne

MaKenna Browne

 PhD candidate


Risha studies non-canonical mechanisms of p53 and Rb-dependent tumor suppression. 


email: Risha.Banerjee@uhn.ca

Jiyeon Park

MaKenna Browne

Nathan Symss

 PhD candidate


Jiyeon studies the epigenetic regulation of SMARCB1 and its role in epithelioid sarcoma. 


email: Jiyeon.Park2@uhn.ca

Nathan Symss

MaKenna Browne

Nathan Symss

 Masters student


Nathan studies the microenvironmental determinants of sarcoma metastasis to the lung. 

email: NathanDavidson.Symss@uhn.ca



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